The first GWAS compared 355 chronic HBV carriers with HCC and 360 chronic HBV carriers without HCC, all of Chinese ancestry, through genotyping 440,794 SNPs and identified one intronic SNP (rs17401966) in KIF1B (kinesin family member 1B) on chromosome 1p36.22 that was associated with HBV-related HCC (joint OR, 0.61) [20]. Here, KIF1B is linked to hepatocellular carcinoma.