Here, we found that both the mRNA and protein levels of p62 in metastatic group (SKBR-3, MDA-MB-231, BT-549 and SUM149) were much higher than that in non-metastatic group (MCF-7 and MCF-10A), indicating that the expression level of p62 positively correlated with the invasive phenotypes of breast cancer (Figure 2A and B). This evidence concerns the gene SQSTM1 and breast cancer.