The mean (standard deviation) CYFRA 21-1/CEA ratio of the MPM patients was 1078 (2650), which was significantly greater than that of Lung cancer 47 (206) (p = 0.04) and Others 51 (267) in the complete-case dataset (p = 0.04) (Fig 3). This evidence concerns the gene CEACAM5 and lung carcinoma.