Specifically, the effects of ARID1A versus ARID1B loss on the accessible genome (Figure 1A) are consistent with a higher frequency of ARID1A mutations in colorectal and ovarian carcinoma (Cancer Genome Atlas Network, 2012; Jones et al., 2010; Wiegand et al., 2010). The gene discussed is ARID1B; the disease is ovarian carcinoma.