MBP and brain ischemia: In order to determine the effect of n-3 PUFAs supplementation on white matter recovery in aged mice, MBP (a marker of mature oligodendrotytes) and SMI-32 (a marker of nonphosphorylated neurofilament associated with axonal damage [38, 39]) were co-immunolabeled using brain sections harvested at 56 days after cerebral ischemia (Fig. 5A).