IDH1 and glioma: We used the Heidelberg brain tumor classifier to assign tumors into following subgroups: H3G34R/V (n = 51), H3K27M (n = 119), HGG WT (n = 156), IDH1 (n = 36), low-grade glioma (LGG)-like (n = 27), pleomorphic xanthoastrocytoma (PXA)-like (n = 43), and “other” (n = 9) (Figure S2A), visualized by hierarchical clustering (Figure 2A) (Table S2).