POMC and neoplasm: The location of bronchial NETs is the most important predictor of symptoms; central tumours frequently produce symptoms while those located more peripherally are more frequently picked up incidentally when imaging for other reasons [79].Thymic carcinoids are frequently functional and may secrete a wide range of hormones; they are responsible for a significant proportion of cases of Cushing’s syndrome due to ectopic ACTH secretion [80] [81].