MTHFR and ischemic stroke: We investigated four single nucleotide polymorphisms in the MTHFR 3′-UTR [2572 C > A (rs4846049), 4869 C > G (rs1537514), 5488 C > T (rs3737967), and 6685 T > C (rs4846048)] to elucidate associations between ischemic stroke prevalence and prognosis.