TLR7 and hepatocellular carcinoma: As for disease progression, the possible influence of TLR7 rs179009 on the development from CHB to HCC in men was confirmed by haplotype CTA and CTG distribution in patients with HCC compared to those with CHB (P < 0.0001 for haplotype CTA; P = 0.003 for haplotype CTG) (Table 6).