In PTCs, HIF‐1α has been involved in regulation of hypoxia‐induced cell responses including VEGF‐A synthesis, glucose consumption, major histocompatibility complex class I‐related chain expression, in vitro epithelial‐to‐mesenchymal transition, renal fibrosis, and apoptosis (Biju et al. The gene discussed is HIF1A; the disease is renal fibrosis.