THY1 and amyotrophic lateral sclerosis: To study the effect of Thy-1 signaling on astrocytes developing under the ALS neuroinflammatory conditions, the transgenic mouse carrying the human G93A mutated super oxide dismutase 1 (hSOD1G93A) was employed, the most widely used ALS model [1, 3, 33, 36, 39, 41–43].