HMGCS1 and cancer: Some of the deregulated genes had no known deregulation linked with cancer, including several genes that belonged to the Lipoprotein signaling and cholesterol metabolism pathway (DHCR7, CYP51A1, NSDHL, HMGCS1, IDI1, CNBP, APOL1, SREBF1), and a few from other pathways, like RHOU (Wnt signaling pathway) and EPDR1 (Cancer pathway).