SFRP1, from the Wnt pathway, was strongly down-regulated in all CRC samples of this study, like most of the genes from the pathway, as opposed to the WNT2 and the CCND1 genes, which were increased in more than 75% of the CRC samples, agreeing with previous results [39, 40]. The gene discussed is WNT2; the disease is colorectal carcinoma.