Release of apoptotic proteins like AIF (Apoptosis Inducing factor), Endo-G (Endo nuclease-G), Bax (bcl-2 associated X), Bcl-2 (b-cell Lymhoma-2) and caspases has been well demonstrated by our group during drug induced hepatotoxicity and hyperglycemia under in vitro conditions [14], [15], [34]. The gene discussed is BAX; the disease is Hyperglycemia.