The BRCA2 mutation c.7480C>T is enriched in Korean familial BC patients [49], and Wong et al. reported four recurrent mutations in BRCA1 (p.Y1127* (c.3381T4A), E23Rfs*18 (c.67_68delinsAG), p.E1112Nfs*5 (c.3333delA), p.T1691K (c.5072C4)) and one BRCA2 mutation (p.C161W (c.483T4G)) in a population from Singapore [50]. Here, BRCA1 is linked to breast cancer.