The distribution of allelic frequencies of MMP3–1171 5A and 6A alleles were found to be 0.58 and 0.42 in controls, compared with 0.51 and 0.49 in patients respectively, showing an increased frequency of 6A-allele of MMP3 (OR 1.30, 95% CI 1.04–1.64, p<0.023 in BC patients (p = 0.023) as summarized in Table 4. Here, MMP3 is linked to breast cancer.