Since then overexpression of ABCB1 and other ABC transporters—such as ABCC1, ABCC2, ABCG2—has been reported by various groups in epileptogenic brain tissue of patients with refractory epilepsy [4,5,6,7] and in rodent as well as in mice models of temporal lobe epilepsies [4,5]. Here, ABCG2 is linked to temporal lobe epilepsy.