GRHL2 and neoplasm: GRHL2 is highly expressed in liver metastases of PDAC (Fig. 1D) (7/7: 100%, high group), and notably, GRHL2 expression in liver metastasis is significantly higher than in paired primary tumor obtained from the same PDAC patient (n = 7) (P = 0.017; chi‐square test; Fig. 1E).