MYC and neoplasm: BL also occurs worldwide at lower incidence, and in these cases, known as sporadic BLs (spBL), EBV is found in 15–85% of tumours, varying by geographical region.1 The genetic hallmark of all BL is the chromosomal translocation between the c-MYC gene and a constitutively active immunoglobulin (Ig) gene promoter/enhancer.