MMP2 and preeclampsia: Invasion-related genes such as transcription factor Snail [6], matrix metalloproteinase 2 (MMP2) [7] and matrix metalloproteinase 9 (MMP9) [8] have been reported to play critical roles in EVT invasion and dysregulations of these genes may contribute to the etiology of preeclampsia and IUGR [9–11].