PLP1 and myeloid sarcoma: It is noteworthy that there are some auto-antigens in the brain including Myelin Basic Protein (MBP), proteolipid protein (PLP), myelin oligodendrocyte glycoprotein (MOG), myelin associated glycoprotein (MAG), alpha-beta crystalline, and heat shock proteins that induce T cell reactivity and play a crucial role in commencing MS (5-10).