The anti-cancer potential of chrysin has also been‏ reported in a variety of cell lines (28) and animals (29).‏ Other previous studies have shown that chrysin sensitizes‏ apoptosis induced cell death by tumor necrosis‏ factor (TNF), or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in various human cancer‏ cells (30), suggesting the therapeutic potential of the‏ chrysin for treatment of human cancers. This evidence concerns the gene TNF and cancer.