CTSS and cancer: It included a number of genes with obvious cancer relevance including CD44, catenin b1 (CTNNB1), vimentin (VIM), cathepsins B and S (CTSB, CTSS), MMP9, XIAP, JunD, numerous proto-oncogenes (REL, YES, SET, FGR, CRK), and HSP90AA1 (which is a chaperone which stabilizes MIF as a client).