MKI67 and neoplasm: For example, the proliferation tumor module is enriched for mitotic cell cycle-related genes (green, n = 1064 genes; weight01 Fisher test [44], p-value < 2e-17) including the well-known marker of proliferation MKI67, 12 serine/threonine kinases that are used in the calculation of the mitotic kinase score (MKS) [45], and several components of the Minichromosome Maintenance Complex (MCM).