Additionally, GO enrichment tests using the Gene Ontology Consortium database (www.geneontology.org) [171] return an 1.8-fold enrichment (Bonferroni-corrected p = 2.1 ⋅ 10−2) for the term “nervous system development” amongst the 340 genes in the neighborhood of FOXO1/CARHSP1/PBX3, and a 2.7-fold enrichment (corrected p = 1.2 ⋅ 10−3) for the same term among the 104 genes for which we found associations with glioma. The gene discussed is PBX3; the disease is central nervous system cancer.