In addition to that, a recent publication uncovered ACSL1 (an isozyme of Acyl-CoA synthetase) and SCD (Stearoyl-CoA-desaturase 1) as part of a metabolic network that increased energetic efficiency in CRC-derived cells together with the promotion of migratory and invasive capacity [6]. The gene discussed is ACSL1; the disease is colorectal carcinoma.