It has been reported that the platelet receptors C-type lectin-like receptor 2 (CLEC-2) [20], P-selectin [21], and integrins α6β1 and αIIbβ3 [22,23] support interaction with tumor cell through the binding of podoplanin, P-selectin glycoprotein ligand-1 (PSGL-1), A disintegrin and metalloproteinase domain-containing protein 9 (ADAM-9), and fibrinogen/αvβ3, respectively. The gene discussed is SELPLG; the disease is neoplasm.