Moreover, several soluble factors of mesothelial origin have been found to stimulate other vital elements of ovarian cancer cell progression, including proliferation (CXCL8/IL-8, IL-6 [104]), migration (CXCL12/SDF-1 [105], HA [106]), and invasion (LPA [103]). The gene discussed is CXCL12; the disease is ovarian carcinoma.