CXCL10 and neoplasm: Excessive chronic production of inflammatory cytokines, including TNF-α, IFN-γ, interleukin (IL)-18, and interferon-inducible protein 10 (IP-10), has been recorded in HIV-infected subjects (6–8); among these, IP-10 is functionally categorized as an inflammatory chemokine which attributed to inflammatory disorders, immune dysfunction, and tumor development (9).