We next infected mice by the I.N. route with a lethal dose of LVS (3 × 103 CFUs/mouse) and then treated the infected mice, starting about 1 h post-infection, once daily by I.P. injection with 2.5, 5, or 10 mg AR-13/kg/day in 200 μl PEG (Hoang et al., 2016) for 10 days. Here, AR is linked to infection.