In contrast to current economic evaluations comparing G-CSF vs. non-G-CSFs or long-acting G-CSF (e.g., pegfilgrastim) vs. short-acting G-CSF (e.g., filgrastim) that solely track FN events during chemotherapy cycles (Lyman et al., 2009; Whyte et al., 2011; Fust et al., 2014, 2015; Kulikov et al., 2016), the approach taken in this study broadens the scope to additional CIN complications including incidence of SN, infection and chemotherapy dose delay. The gene discussed is CSF3; the disease is cervical squamous intraepithelial neoplasia.