RAN translation was also reported to occur in other repeat expansion diseases such as spinocerebellar ataxia type 8, ALS and frontotemporal patients (C9ALS/FTD) (DeJesus-Hernandez et al., 2011; Ash et al., 2013; Cleary and Ranum, 2014). This evidence concerns the gene RAN and spinocerebellar ataxia type 8.