Beneficial properties of DASH diet on IR did not confirmed in some clinical trials,(13–16) whereas improvement of homeostasis model assessment of insulin resistance (HOMA-IR) was observed following adherence to DASH diet polycystic ovary syndrome (PCOS) and pregnant women with gestational diabetes.(17,18) Adherence to DASH diet combined with a training program improved insulin sensitivity in patients with hypertension and overweight.(19). The gene discussed is INS; the disease is hypertensive disorder.