One example of this was the work performed by Wang et al. [117], who studied the effect of tyrosol on the expression of HO-1 and Nrf2 activation in C57BL/6 male mice treated with LPS, the predominant pathogen which induces acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). The gene discussed is NFE2L2; the disease is acute respiratory distress syndrome.