KRAS and neoplasm: Similar findings were observed in an A549 (KRAS (proto-oncogene corresponding to the oncogene first identified in Kirsten rat sarcoma virus) mutant cell line) xenograft model with tumor growth inhibition of 92% and 87% at 5.0 mg/kg and 2.5 mg/kg respectively, with inhibition to a lesser degree with a lower dose [28].