With respect to ORO cases, the most important variables were TEMP and SEA-TEMP; for MAY: THERM-AMP and SEA-TEMP, which was similar to ORO; for SLE: RAIN and DTV, and finally for ROC, the most important variables were THERM-AMP and ELEV. Here, C1orf210 is linked to systemic lupus erythematosus.