Focal adhesion kinase (FAK) is an intracellular tyrosine kinase that regulates cellular adhesion, control of cell-extracellular interactions such as cell spreading, migration, metastasis, motility, cancer stem cell self-renewal and survival in many types of cancers and FAK is overexpressed in a number of tumors including CRC [18]. This evidence concerns the gene PTK2 and colorectal carcinoma.