IRAK3 and inflammation: Compared with the WT mice, IRAK-M−/− mice demonstrated more obvious lung inflammation evidenced by more inflammatory cells infiltrated in the airways (BAL total inflammatory cells, neutrophils, and lymphocytes) (Figures 1(a), 1(b), 1(c), and 1(d)) and deposited around peribronchus and vascular (Figure 1(e)).