The results showed that higher hsCRP (P = 0.002, FDR = 0.004), Lp-PLA2 mass (P = 0.016, FDR = 0.016), and Lp-PLA2 activity (P < 0.001, FDR < 0.001) and lower HDL-c (P = 0.012, FDR = 0.016) contributed to the development of MCI in T2DM (Table 6). The gene discussed is PLA2G7; the disease is type 2 diabetes mellitus.