ETFDH and multiple acyl-CoA dehydrogenase deficiency: Glutaric aciduria type II (GA II), also known as multiple Acyl-CoA dehydrogenase deficiency (MADD), is a rare autosomal recessive disorder of fatty acid, amino acid and choline metabolism caused by a defect in the alpha or beta subunit of the mitochondrial electron transfer flavoprotein (ETFA, ETFB) protein or the electron transfer flavoprotein dehydrogenase (ETFDH) protein [1].