TRIM3 and neoplasm: As shown in Fig. 8a, b, the mean tumor volumes in mice injected with TRIM3-overexpressing cells were significantly smaller than those in mice injected with LV-NC-infecting cells (746 mm3 vs. 2128 mm3 for HepG2; 308 mm3 vs. 1286 mm3 for Bel-7402; both P < 0.001).