The mean tumor weights in mice injected with TRIM3-overexpressing cells were also markedly lower than those in mice injected with LV-NC-infecting cells (0.8 g vs. 1.8 g for HepG2; 0.5 g vs. 1.3 g for Bel-7402; both P < 0.001, Fig. 8c). This evidence concerns the gene TRIM3 and neoplasm.