CD274 and cancer: Preliminary outcomes from trials evaluating other non-approved anti-PD-1 (pidilizumab) and anti-PD-L1 (atezolizumab, durvalumab, avelumab and BMS-936559) mAbs are also displaying promising response rates for a range of cancers (Barbee et al, 2015; Rittmeyer et al, 2016; Rosenberg et al, 2016; Seetharamu et al, 2016).