TFAP2B and major depressive disorder: TFAP2B gene variants have previously been related to different personality dimensions in women, namely anxiety, psychasthenia, guilt, depression, impulsiveness, indirect aggression or addictive behavior (Damberg et al., 2000, 2003; Hensch et al., 2008; Nilsson et al., 2009; Nordquist et al., 2009); features that are often present in women with ED.