After triggering the p53-dependent DNA damage response or non-genotoxic activation of p53 they identified two lncRNAs, nuclear enriched abundant transcript 1 (NEAT1) and lincRNA-p21, as p53 targets in primary CLL and in a series of Burkitt's lymphoma cell lines. This evidence concerns the gene CDKN1A and B-cell chronic lymphocytic leukemia.