Among the four most differentially regulated lncRNAs (BALR-1, BALR-2, BALR-6, and LINC00958) high expression of BALR-2 (B-ALL associated long RNA-2), encoded by a locus on chromosome 7q21.2, correlated with a worse overall survival (OS) and a reduced response to prednisone treatment in a large cohort of B-ALL cases. Here, CDK6-AS1 is linked to acute lymphoblastic leukemia.