Considering MM patients carrying t(4;14), it is of relevance the upregulation of lnc-WHSC2-2 that maps intronic and antisense to the translocation target gene MMSET. Notably, the consistent deregulation of lnc-WHSC2-2 in translocated MM resembles that of snoRNA ACA11 that maps in the adjacent 3′ intron of MMSET on the sense strand [122, 123]. The gene discussed is NSD2; the disease is Miyoshi myopathy.