Interestingly, the opposite was found for LAG-3, which was expressed by a larger proportion of T-cells in BPH (median 17.9%) and BPH with concurrent PC (median 33.8%) than in PC lesions (median 8.6% and 2.6% in non-malignant and malignant lesions respectively). This evidence concerns the gene LAG3 and benign prostatic hyperplasia.