There was an increase in the percentage of CD4+ T-cells expressing CD69 in non-malignant tissue of PC patients compared to control tissue and BPH, where a large spread was observed (median 81.7% vs. 46.9% and 53.5% respectively, p = 006, p = 0.008) (Figure 3B). The gene discussed is CD4; the disease is benign prostatic hyperplasia.