The anti-angiogenic activity of AF is due to its ability to bind VEGF-A and VEGF-B, preventing the interaction with VEGF receptors [5]; however, our data indicated that DMGF did not impact VEGF-induced capillary-like tube formation in SVEC4-10 endothelial cells (Figure 2B). Here, VEGFB is linked to atrial fibrillation.