UD acts as a protein-protein antagonist of EphA2 (a receptor kinase) by interfering its phosphorylation mediated by Ephrin-A1, without inhibiting the kinase domain of EphA2, and using a mechanism other than cytotoxicity or anti-proliferative effect in the PC3 human prostate adenocarcinoma cells [90]. Here, EPHA2 is linked to prostate adenocarcinoma.