Compared with human CRC tissue, HCT116 and HT-29 cells exhibited similar HSD17Β mRNA (data not shown) and protein (Fig. 2A) expression (i.e., lack of HSD17Β1, presence of HSD17Β7 and HSD17Β12, and limited HSD17Β2 expression). Here, HSD17B2 is linked to colorectal carcinoma.