HSD17B1 and colorectal carcinoma: Compared with human CRC tissue, HCT116 and HT-29 cells exhibited similar HSD17Β mRNA (data not shown) and protein (Fig. 2A) expression (i.e., lack of HSD17Β1, presence of HSD17Β7 and HSD17Β12, and limited HSD17Β2 expression).