AKT1 and lung adenocarcinoma: NCKU-21 induced apoptosis and inhibited cell migration in the A549 and CL1-5 human lung adenocarcinoma cell lines, the toxicological activities of which may be partially mediated through suppression of PI3K-AKT, increases in AMPK phosphorylation and the p53 protein, and inhibition of gelatinases.