2004; Borg et al. 2010). However, Debniak et al. demonstrated that the common variant N991D is linked with an increased malignant melanoma risk (Debniak et al. 2008; Bougie and Weberpals 2011). Finally, the 5′ UTR polymorphism c.1‐26G>A (rs1799943) of BRCA2 is considered benign (ClinVar), even though Gochhait et al. reported that this polymorphism might regulate the expression of BRCA2, albeit not at a transcriptional level, but at a posttranscriptional level affecting the translational efficiency (Gochhait et al. 2007). The gene discussed is BRCA2; the disease is melanoma.