DYRK1A and Dravet syndrome: Prospects for Dyrk1a inhibition as a molecular therapy for DS will depend on advances in several key areas, including: 1) determining specific dosing regimens and routes of administration that produce dose‐dependent changes in drug concentrations in specific tissues that correlate with concentration‐dependent inhibition of Dyrk1a; and, 2) determining the extent to which therapeutic efficacy of treatment varies as a function of developmental timing and duration of treatment and the temporal profile of tissue‐specific inhibition of Dyrk1a.